Understanding how reduced mechical load / shear may affect vascular function 

ISS In vitro Experiment in KUBIK incubator studying how microgravity affects smooth muscles in veins. The results of the experiment showed that smooth muscle contractability was decreased in microgravity due to calcium channel down regulation. A similar effect was also observed in an animal model. Data from this study is relevant to understanding how reduced mechical load / shear may affect vascular function.